VISDB Viral Integration Site DataBase

VIS ID

TVIS10017618

Fusion event

HBV-SLC5A6 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;

Start

1862

Integrated sequence

GGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTG| |TTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTC

Chromosome

chr2

Cytoband

p23.3

Reference genome

Start

End

27423375/27200507 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-24-3p ; hsa-mir-27b-3p ; hsa-mir-3138 ; hsa-mir-636 ; hsa-mir-1294 ; hsa-mir-139-3p ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-4327 ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-4524a-3p ; hsa-mir-424-3p ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6515-3p ; hsa-mir-877-3p ; hsa-mir-4802-5p ; hsa-mir-4712-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6813-5p ; hsa-mir-6085 ; hsa-mir-577 ; hsa-mir-4524b-3p ; hsa-mir-1252-3p ; hsa-mir-3662 ; hsa-mir-548c-3p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7d-5p ; hsa-let-7g-5p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7c-5p

Nearest miRNA

hsa-mir-1301/Upstream/1871786; hsa-mir-10b/Downstream/795860;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/50161, chr2-CpG: 116/Downstream/11057

Upstream sequence

catgctcagctaattttcatatttttagtagagatggagttttgccatgttgcccaggctgatctcaaattcttgatctcagtgatccacctgcctcagc

Downstream sequence

CTCCTTGTCTCTGCTGTCCCCCAGCACACCATTCCTCGGCTTCTCAGGAAACAGGCCAGTGTCGAGGTGGTCCTGCAAACACAGAGCCAAAGGGGTGGAA