VISDB Viral Integration Site DataBase

VIS ID

TVIS10017619

Fusion event

HBV-USP34 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1822

Integrated sequence

TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAG

Chromosome

chr2

Cytoband

p15

Reference genome

Start

End

61634179/61407044 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-23a-3p ; hsa-mir-19b-3p ; hsa-mir-127-5p ; hsa-mir-485-5p ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-1301/Upstream/1019599; hsa-mir-10b/Downstream/798782;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/228818, chr2-CpG: 154/Downstream/63178

Upstream sequence

tccctccctccctcccccttacctccctgccttccttccGGCGGGCGTACTTGCGGGCGGGCGGGGCTGCgggggggcgtgggtagggggggggggtggg

Downstream sequence

TTAGACATGTTCAGTTAGTAGCACAATGCCTGGCATATGTAGATAATTAAAAGGATCTCAgccaggtgcagtggttcacacctgtaatcccaacactttg