VISDB Viral Integration Site DataBase

VIS ID

TVIS10017620

Fusion event

HBV-PARD3B integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1769

Integrated sequence

ACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTT| |GTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGC

Chromosome

chr2

Cytoband

q33.3

Reference genome

Start

End

206398012/205533288 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6873-3p ; hsa-mir-3941 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6758-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3180-5p ; hsa-mir-4642 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-4267

Nearest miRNA

hsa-mir-10b/Upstream/16400177; hsa-mir-1244-1/Downstream/1249946;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/987101, chr2-CpG: 91/Downstream/148591

Upstream sequence

gggagggggggggggggggggggggggggggggggggggggggagggggggggggggggggggggggggggggggaggggggggggggaggggggggggg

Downstream sequence

GGAGGAACACCCCAGTGCCCAGATAAGCTGTTTTATACCGTGATGACAGAAGACAAATAATGAAGTTCATATTCTGTACAGAACTTGAAGATGGCTTATT