Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017622
Fusion event
HBV-ITIH3 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1749
Integrated sequence
TTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGG| |AGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGT
Host Sequence
Chromosome
chr3
Cytoband
p21.1
Reference genome
Start
End
52841132/52807116 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/512808; hsa-mir-12124/Downstream/39347;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/36004, chr3-CpG: 72/Downstream/90094
Upstream sequence
TCCACCACCCCCTGCTAAACTCACCTCCATGCTGGCTTGTTTGACCTTCTGCACCTCAAACACCCTGTGCGGGGTCCCCTGCTGGTAGTTGATGTAGTTC
Downstream sequence
TACAAGGtctccaaggtggactacagggtgagagtctaaggaggctcttgagggatttagaaaaatcccaggacaggagatccatgggggtcacaggaaa
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.