Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017626
Fusion event
HBV-MCCC1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;Polymerase;
Start
1608
Integrated sequence
CCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCA| |TGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTT
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
End
182735112/183017324 (Hg38)
Location type
Exonic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7g/Upstream/6502173; hsa-mir-1224/Downstream/869476;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/36381, chr3-CpG: 40/Downstream/47062
Upstream sequence
GCTGTCTCAGTGGGGATGCTCCAAGGTAGTTCCTTCGATGGGATTGGTAGATCAGGTCACCTGGCAGTGCCCTGAAAAATCAGAGTTGAGAGCAGGTGCA
Downstream sequence
CTTTGACAAACACCTTGAGATTCAGTGTGACAGGTTAATATTTGAAAACACAgaggtcctagatatgttcatctgcttcattatagtaaccattttactg
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.