Fusion event
HBV-ALB integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
GAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACC| |TCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTC
End
74283335/73417618 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/7140690; hsa-mir-1243/Downstream/3155950;
Upstream sequence
CTACCTCTGAATCACAGTAAAGAGGAGGTGAGTTTATGGAACAGCAGTTGGAGGCAAAGTCTGAGTGCTTGTTAACCAGCTTTGCCAGTTCCGTGGGTGT
Downstream sequence
AAATGTTGTAAACATCCTGAAGCAAAAAGAATGCCCTGTGCAGAAGACTATGTGAGTCtttaaaaaaatataataaattaataatgaaaaaattttaCCT
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.