ALB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017631
Fusion event
HBV-ALB integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
Polymerase;
Start
1226
Integrated sequence
AACAATATCTGAACCTTTACCCCGTTGCTCGGCAACGGTCAGGTCTTTGCCAAGTATTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCA| |TCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGGGCGAAACTGCTC
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74284004/73418287 (Hg38)
End
74284004/73418287 (Hg38)
Location type
Exonic
Target gene
ALB
miRNAs that regulate target gene
hsa-mir-492
Nearest miRNA
hsa-mir-12113/Upstream/7141359; hsa-mir-1243/Downstream/3155281;
Nearest TSS
ENST00000502981/Upstream/281; ENST00000508932/Downstream/994;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/158874, chr4-CpG: 20/Downstream/202040
Upstream sequence
ATATAAAATATCGCATGATAATACCATTTTGATTGGCGATTTTCTTTTTAGGGCAGTAGCTCGCCTGAGCCAGAGATTTCCCAAAGCTGAGTTTGCAGAA
Downstream sequence
GGAGAGACAAATCAAGAAACAAACGTGAGGAGTATTTCATTACTGCATGTGTTTGTAGTCTTGATAGCAAGAACTGTCAATTCAAGCTAGCAACTTTTTC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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