VISDB Viral Integration Site DataBase

VIS ID

TVIS10017634

Fusion event

HBV-CLK4 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;Polymerase;

Start

1531

Integrated sequence

CCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCT| |CTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGA

Chromosome

chr5

Cytoband

q35.3

Reference genome

Start

End

178032339/178605338 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-550b-2-5p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-4252 ; hsa-mir-6889-3p ; hsa-mir-149-5p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-5698 ; hsa-mir-891a-3p ; hsa-mir-143-5p ; hsa-mir-6499-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-5693 ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-216a-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-4485-5p

Nearest miRNA

hsa-mir-10397/Upstream/1975838; hsa-mir-1229/Downstream/1192940;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/14669, chr5-CpG: 99/Downstream/21093

Upstream sequence

GCAATCAGACCCTTTCATAACTCTTTCAAAATACGGTAGTTTTGACCAACAGCTTTCCAGCTTAATAACGCAGTTATCATTGGTACTCTTTAGCCAAGAT

Downstream sequence

AATATTCGTTCCATCATTGCCAGGTGCTCTTTACTATCATGAGTCTAAAACATGTAAGAAAAAGAAATTTAGTACTCTCCATTTCCCTACAAACACATTA