VISDB Viral Integration Site DataBase

VIS ID

TVIS10017635

Fusion event

HBV-FKBP5 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

706

Integrated sequence

CATCCCATCATCTTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTA| |GGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAATCCCTTTTTACCGCTGTTACCAA

Chromosome

chr6

Cytoband

p21.31

Reference genome

Start

End

35543563/35575786 (Hg38)

Location type

3UTR

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-93-3p ; hsa-mir-328-3p ; hsa-mir-22-3p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-6516-5p ; hsa-mir-550b-2-5p ; hsa-mir-4443 ; hsa-mir-455-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1243 ; hsa-mir-3654 ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-302c-5p ; hsa-mir-7106-5p ; hsa-mir-6878-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-6133 ; hsa-mir-765 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-539-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-6760-5p ; hsa-mir-7977 ; hsa-mir-3166 ; hsa-mir-3664-3p ; hsa-mir-5690 ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-4666a-5p ; hsa-mir-4740-5p ; hsa-mir-4272 ; hsa-mir-6816-3p ; hsa-mir-3169 ; hsa-mir-8080 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-511-5p ; hsa-mir-28-5p ; hsa-mir-3139 ; hsa-mir-3190-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-3926 ; hsa-mir-4684-5p ; hsa-mir-4786-5p ; hsa-mir-548c-3p ; hsa-mir-548s ; hsa-mir-5589-5p ; hsa-mir-6771-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-708-5p

Nearest miRNA

hsa-mir-1236/Upstream/105207; hsa-mir-10398/Downstream/88931;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/63409, chr6-CpG: 165/Downstream/112044

Upstream sequence

TTACAAGTAACATCTCCTATAAAATACTTCAGTACCTGGAACAGTTTTTGCTTCTCCGGAACTTTATTTTTAAAATGCCTGCGGGAAGCAGTGCTTATCG

Downstream sequence

TTGAGGAGGGGCCGAGTTCACTGGGACTCTTCCCTCCTTGGCGTGGCGTCATACGTGGCCCTCAGGTTTCTCTTCTTCCATTGCTTGACTGTCTGTTCCT