Fusion event
HBV-XPA integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCT| |TGTTTTGCTCGCAGCCGGTCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTG
End
100459540/97697258 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7a-1/Upstream/333577; hsa-mir-12126/Downstream/531891;
Upstream sequence
GCAAGTGGTTTTATATCGCATCGGCCTTTCGAAACGAGGAGTACAATAAGTCGGTTCAGGAGATCCAAGCAACCTTCTTTTACTTCACCCCCAACAAGAC
Downstream sequence
ttttttttgagatggagtttcactctgtctcccaggctgaagtgcagtggcatgatctcggctcacttcaacctctgctgcctgagttcaagcgattctc
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.