Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017638
Fusion event
HBV-C8G integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;Polymerase;
Start
1543
Integrated sequence
AATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGG| |TCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCC
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
End
139840199/136945747 (Hg38)
Location type
Exonic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7a-1/Upstream/58944; hsa-mir-3621/Downstream/223439;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/759, chr9-CpG: 33/Downstream/4093
Upstream sequence
ttatgttcattgtaaaatatttgaaaagtacaaataagtggaaaaagtcatccacaatccATTATTATATTAAGGCTATTACCAAttttctgtctttttt
Downstream sequence
ACTCTTCCTCGGTCAGCTTATTCCACCTCCAGCCATTTCCTTACTTCAACCTCATACTTCACCCAGGACCTCCAGGGCCATGTGGAGCCAGTGCAATCCT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.