SACM1L _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017641
Fusion event
HBV-SACM1L integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Region type
core protein;X protein;
Start
1828
Integrated sequence
ACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCAC| |CTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTG
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
End
45785190/45743698 (Hg38)
Location type
3UTR
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/881717; hsa-let-7g/Downstream/2105857;
Upstream sequence
AAGGTAGAAATCTTATAAGCTTTACAACTCTGAAAACATACCTTAACTGTCACAGCAACTAATTCAAAACAAACAAAAAATTCTGCTAAAACCAACAAAG
Downstream sequence
GGAAGATTCCATTGTGCAGAACTGGAGTCTTTACTGACCCGCTTTCCACATCAGCCCAAGGTCTTTTTAATGCCTTTATCCAAAAGCACATCTTGTGCTC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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