VISDB Viral Integration Site DataBase

VIS ID

TVIS10017642

Fusion event

HBV-NIPAL3 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1670

Integrated sequence

CGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGA| |CTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTG

Chromosome

chr1

Cytoband

p36.11

Reference genome

Start

End

24777476/24450986 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1303 ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-7-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-6807-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-1343-5p ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-3675-5p ; hsa-mir-496 ; hsa-mir-552-5p ; hsa-mir-6763-5p ; hsa-mir-6825-5p ; hsa-mir-6890-5p ; hsa-mir-939-5p

Nearest miRNA

hsa-mir-12136/Upstream/521839; hsa-mir-101-1/Downstream/468359;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/34437, chr1-CpG: 108/Downstream/51389

Upstream sequence

GAAATTTATATCAGTGATCATGGATAAAAAATTTAAGTATTCTGTGCTGAAATTTGACAGGCATCCAGGGAAACAAAAATTGTTCGGAAAGGAGAACTAA

Downstream sequence

AAACTAAAGCCCGTGTGAACTGCATTCTTAGAAGCTGAATCTTCTCAGAAAGTAAGCAAACCAGCTAGTTCACTGTGAATTCATAAAAGCCAAGTTACAA