Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017643
Fusion event
HBV-AGBL4 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Region type
X protein;
Start
1678
Integrated sequence
GTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGC| |AATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGA
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
Start
End
49090095/48624423 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/4078871; hsa-mir-101-1/Downstream/2435414;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/152024, chr1-CpG: 69/Downstream/152096
Upstream sequence
ATTCCATCCTATCAACAATTAACAAGTAGCCAGGGACAGAATTTAGGCAGCTCCAttttcttttttttttttttttttggagacacagtctcgctctgtc
Downstream sequence
AGATTCTCTTTTGTCTGTACCAACAGACTTGTTCCTTCTAGCACTTCTATGCTCTAACAGTTACAAAAGACATCATCTTTAAATCCTGCCGTCTCTCTAG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.