VISDB Viral Integration Site DataBase

VIS ID

TVIS10017644

Fusion event

HBV-HFM1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1808

Integrated sequence

CAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT

Chromosome

chr1

Cytoband

p22.2

Reference genome

Start

End

91852971/91387414 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-218-5p ; hsa-mir-2681-5p ; hsa-mir-4724-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-551b-5p

Nearest miRNA

hsa-mir-101-1/Upstream/5029727; hsa-mir-11399/Downstream/2459418;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/365164, chr1-CpG: 62/Downstream/16905

Upstream sequence

ATACCCTGCCCTGAGCCAATCAAAAAAAGCTTTTCACCTGCCATTGGCCCACCCACCAATCAGAGGAAGTGTCTGGAGGGAGAGCCCTCCCCTGGCCAAT

Downstream sequence

TGGGCCAAGGGAGTGAAGGAAAGAGCCTCTCCTGCTTCATAACAATTGTACCCTCTCTCCTCTCATCCCTCACGCCTATTTCCTCCCCTGCATCCACATG