VISDB Viral Integration Site DataBase

VIS ID

TVIS10017647

Fusion event

HBV-URB2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1794

Integrated sequence

CTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAAT| |TGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTT

Chromosome

chr1

Cytoband

q42.13

Reference genome

Start

End

229769463/229633716 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-423-3p ; hsa-mir-15b-5p ; hsa-mir-92a-3p

Nearest miRNA

hsa-mir-101-1/Upstream/1171564; hsa-mir-1182/Downstream/1386112;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/7164, chr1-CpG: 171/Downstream/433031

Upstream sequence

CTCAGTAAACAGAAGCAGGCAAATGGCTGGCCCCCGGCCTGCTTCAGATTATGGCTTCCACCAGGGACACCAGCTGCCTGAAAGTGGTACCTTTCAGGAC

Downstream sequence

AGGGACTCCATTTCCTTGGCAGGGAGCACAGTGGCAGGAACTAACTTCCTTCTGGAACTCCTCCAGTGCCTGCTTCATGTTCTGCCTCACTGTGCTGGAA