Basic Information
VIS ID
TVIS10017657
Fusion event
HBV-LINC00907 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
DQ089769.1
Region type
X protein;
Start
1768
Integrated sequence
GACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTT| |TGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAG
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
39977347/42397382 (Hg38)
End
39977347/42397382 (Hg38)
Location type
ncRNA
Target gene
LINC00907
Nearest miRNA
hsa-mir-1-2/Upstream/2720603; hsa-mir-122/Downstream/2572700;
Nearest TSS
ENST00000575820/Upstream/171418; ENST00000591940/Downstream/576713;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/2555517, chr18-CpG: 180/Downstream/2281636
Upstream sequence
ATGGAAATGGGGGCTcagtgctggagttcagactcatgtctgactggctccaagcctgtgctccttctgttatgcccggctgtctcccAGGAAGCAGGGG
Downstream sequence
GTCACCAGAACCAAGAAATCTGTTTACCTTTAATGGAAGATTTAAGCAGATTAAATTTTCTTCATATAATCTCTCCAATATTTTGCAAATTTTGTGTCTG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate