VISDB Viral Integration Site DataBase

VIS ID

TVIS10017658

Fusion event

HBV-PARD6G integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1801

Integrated sequence

CATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTG| |TTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA

Chromosome

chr18

Cytoband

q23

Reference genome

Start

End

77968329/80210446 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-4446-5p ; hsa-mir-223-5p ; hsa-mir-4524a-3p ; hsa-mir-4740-3p

Nearest miRNA

hsa-mir-1-2/Upstream/7357064;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/49740, chr18-CpG: 189/Downstream/35699

Upstream sequence

tattatatatttacatattatatatatcttaatgtataaatatatatTCTATAACTATATCATAGAAATATATATGCAATTGAAAACAAGCATATCTAGA

Downstream sequence

cagcctgggagggagcagaaccagtctggaagttccccaaagcccacactcaggactgtcatcgtcagacctgtcttgcagctccaggaaaagcccttct