VISDB Viral Integration Site DataBase

VIS ID

TVIS10017662

Fusion event

HBV-CPNE5 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1793

Integrated sequence

CCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAA| |TTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT

Chromosome

chr6

Cytoband

p21.2

Reference genome

Start

End

36805554/36837778 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-122-5p ; hsa-mir-6763-3p ; hsa-mir-7977 ; hsa-mir-7704 ; hsa-mir-615-5p ; hsa-mir-6784-5p ; hsa-mir-5587-3p ; hsa-mir-4532 ; hsa-mir-4707-5p ; hsa-mir-4738-5p ; hsa-mir-6890-5p ; hsa-mir-6715b-3p ; hsa-mir-4437 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-1827 ; hsa-mir-371a-5p ; hsa-mir-6840-3p ; hsa-mir-6715a-3p ; hsa-mir-5088-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p

Nearest miRNA

hsa-mir-1236/Upstream/215266; hsa-mir-10398/Downstream/717587;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/153420, chr6-CpG: 147/Downstream/1327

Upstream sequence

ggaacaccagggactaaactctgacctccattctttgctctcagtttcttcctgaggggcctggccagaccttaatgttcctttctgcggaccccaagtt

Downstream sequence

AAGGATCCCAAGACAACTGAAGATGACAGGCATGATTGAAGGCTGGGAGGGAGTGCCAGGCGCAGGGATGTGCGTGCAGGAGAAGGGTGGGGAGGCCGTG