VISDB Viral Integration Site DataBase

VIS ID

TVIS10017663

Fusion event

HBV-PRIM2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

core protein;

Start

1919

Integrated sequence

CTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATA| |AAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGTGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGA

Chromosome

chr6

Cytoband

p11.2

Reference genome

Start

End

57257381/57392583 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-4266 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6894-5p ; hsa-mir-7160-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-7162-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-890

Nearest miRNA

hsa-mir-10398/Upstream/2371; hsa-mir-10524/Downstream/13984377;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/170070, chr6-CpG: 35/Downstream/461293

Upstream sequence

gaactatagtaaccaaaacagcatggtactggcataaaacaaacacagaccaatggaacagaatagagaaccagaaataaattcatacatctacaatgaa

Downstream sequence

TTTCATGGAATAGAAGGGCCACTAATAGCCTAGAGAGGGAGAAGGAAAATATTCGTTTTTTTTTTGTGGATATCCaaatttttatttatttttattattt