VISDB Viral Integration Site DataBase

VIS ID

TVIS10017665

Fusion event

HBV-HIVEP2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1751

Integrated sequence

ACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAG| |ATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTC

Chromosome

chr6

Cytoband

q24.2

Reference genome

Start

End

143220068/142898931 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-130b-3p ; hsa-mir-598-3p ; hsa-mir-484 ; hsa-mir-10b-5p ; hsa-mir-136-5p ; hsa-mir-298 ; hsa-mir-5684 ; hsa-mir-5700 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4662a-3p ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-302c-3p ; hsa-mir-372-3p ; hsa-mir-520e ; hsa-mir-520b ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p

Nearest miRNA

hsa-mir-10398/Upstream/2215048; hsa-mir-1202/Downstream/8203744;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/596615, chr6-CpG: 60/Downstream/27741

Upstream sequence

CACATATCTACCCATGTATCTTGCCAGAAGGAACTTATCTTTAAAAGTATTATGGTGAACATGGAAACATACTAGTCATATAAGAGACATAGTTTATAAA

Downstream sequence

CTGTAATTGTCTGCACACCATGTCTCCCAAATCCGGGCTTGGCTTCCTCTGTATCATTCTTGTGAGGCTGCCTGAGAGATATTTGTAAAATGCTAATCGG