VISDB Viral Integration Site DataBase

VIS ID

TVIS10017666

Fusion event

HBV-COG5 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

core protein;X protein;

Start

1827

Integrated sequence

GACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTT

Chromosome

chr7

Cytoband

q22.3

Reference genome

Start

End

107027498/107387053 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-320a ; hsa-mir-3978 ; hsa-mir-4261 ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-610 ; hsa-mir-181a-2-3p ; hsa-mir-497-3p

Nearest miRNA

hsa-mir-10525/Upstream/4915522; hsa-mir-10399/Downstream/7266292;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/217169, chr7-CpG: 59/Downstream/176616

Upstream sequence

attactgtgaaaagtcatcatcaggaaggctagggcccctgtcccccatctcagtaggtgggtagaatcctaacttgtcaactcacaaacacagctggcc

Downstream sequence

gcaagtggcattagaaggggagttcttagcttgcccagtaatgcaagattgacaaggcaatcgagtatttcttttaacacttataaaaagataaagcatt