VISDB Viral Integration Site DataBase

VIS ID

TVIS10017667

Fusion event

HBV-AGK integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1754

Integrated sequence

TAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATT| |AGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATG

Chromosome

chr7

Cytoband

q34

Reference genome

Start

End

141353038/141653238 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-7-5p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-378a-3p ; hsa-mir-526b-5p ; hsa-mir-3682-3p ; hsa-mir-5571-5p ; hsa-mir-6734-5p ; hsa-mir-629-3p ; hsa-mir-6834-5p ; hsa-mir-1226-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-582-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6875-5p ; hsa-mir-4419a ; hsa-mir-5695 ; hsa-mir-3126-5p ; hsa-mir-519d-5p ; hsa-mir-3691-3p

Nearest miRNA

hsa-mir-10399/Upstream/2609081; hsa-mir-11400/Downstream/821289;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/101566, chr7-CpG: 81/Downstream/48394

Upstream sequence

tgactttgtcaaagaccagtggttttaggtgtgcagctttatttctgggttttctattccgttccgttggtctgtatgtctgtACAACATCTTGTATCCC

Downstream sequence

CCCACGGTGGGCTTAGCCTGCCTAGGCCCTTCCATTTCTCTTCTTTGACCGTGCTAGGAATTCCAGGAAAGTGCATTCCTGCCCTGGTGACCTTTTCCTA