VISDB Viral Integration Site DataBase

VIS ID

TVIS10017671

Fusion event

HBV-PUM1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;Polymerase;

Start

1505

Integrated sequence

TGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCC| |GTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTC

Chromosome

chr1

Cytoband

p35.2

Reference genome

Start

End

31425556/30952709 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-423-3p ; hsa-mir-151a-3p ; hsa-mir-181a-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-296-3p ; hsa-mir-324-3p ; hsa-mir-324-5p ; hsa-mir-186-5p ; hsa-mir-99a-5p ; hsa-mir-568 ; hsa-mir-508-3p ; hsa-mir-219a-5p ; hsa-mir-4445-5p ; hsa-mir-4782-3p ; hsa-mir-6766-3p ; hsa-mir-142-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-340-5p ; hsa-mir-6809-5p ; hsa-mir-7112-5p ; hsa-mir-4708-3p ; hsa-mir-651-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-335-3p ; hsa-mir-4528 ; hsa-mir-4283 ; hsa-mir-760 ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-3149 ; hsa-mir-5004-3p ; hsa-mir-3618 ; hsa-mir-4696 ; hsa-mir-571 ; hsa-mir-451b ; hsa-mir-4704-5p ; hsa-mir-548e-5p

Nearest miRNA

hsa-mir-12136/Upstream/213477; hsa-mir-101-1/Downstream/805951;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/43590, chr1-CpG: 60/Downstream/112856

Upstream sequence

ATTGCAGCTCCGAATATTCAGATGGGGACAGTGAAGCACAGATCTCAGGAGTCCTAAGTATTCATGGCTACCACTAAGTTGGATAGGTGAGTAGGAAATG

Downstream sequence

CTAGAAGGGGTGAAAGCCTATagaaaggaggaaaagagagactgaaagatgaagtagaaaggaaatgcatgacaaagagtgagagagatggagagagaca