Fusion event
HBV-SLC30A10 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
TAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCT| |AGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATG
End
220100372/219927030 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/7849345; hsa-mir-1182/Downstream/190823;
Upstream sequence
TCACACCAACATAGTAAACATATTCCTGGGCTGATCCACAACATGACTGCCCGCTGCTGTGACCTGCCATTTCCAGAACAGGCCTGCTGTGCAGAGGAGG
Downstream sequence
AGGTGAGTGTGTGGAGTCTAGTCTCCAGAGGAATGCAGGGGAGGGGAGGGAAAGAGCTAGAACTGCAGGCCACCCCTTCTCTTTAGTACCTCAAACCAGC
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.