Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017676
Fusion event
HBV-RBP4 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;Polymerase;
Start
1433
Integrated sequence
ACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCC| |GTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCTCT
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
Start
End
95360910/93601153 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-107/Upstream/4008326; hsa-mir-1287/Downstream/2463162;
Nearest CpG islands
chr10-CpG: 106/Target, None/Upstream, None/Downstream
Upstream sequence
tgctatgttgatgtgctgcacccattaactcgtcatttaacattaggtatatctcctaatgctacccctccccgctccccccaccccacaacaggccccg
Downstream sequence
CTTTCTGTATTCTCCATGTGCCATGGGTTTACCTGTTCCTGTGGGTGGTATTCCTCAGAGACCATGGATATATCTGATCCTGCAGGTAGTTTTCCAGGAA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.