VISDB Viral Integration Site DataBase

VIS ID

TVIS10017680

Fusion event

HBV-CMAS integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1798

Integrated sequence

AGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGT| |CTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGG

Chromosome

chr12

Cytoband

p12.1

Reference genome

Start

End

22202439/22049505 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-34a-5p ; hsa-mir-320b ; hsa-mir-421 ; hsa-mir-320a

Nearest miRNA

hsa-mir-1244-3/Upstream/4376111; hsa-let-7i/Downstream/2162916;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/2850, chr12-CpG: 102/Downstream/284396

Upstream sequence

GTATGACAGGCTCATCAACTCACTCAATAAACGTAAGAGATAAAATAAAGTGCTAAGGCAACCAAACCAAAAGCAGCAAATCTTCAACTGAGGTAAAATT

Downstream sequence

AAAAGTTGTAGCCAACGGAATTCATTTTAAGTTTTTCTATCTTAGTGCACATAAAATAGTATACACTTAAAATTATTTACTGTTCTCAGTAGTTAAAAAG