VISDB Viral Integration Site DataBase

VIS ID

TVIS10017681

Fusion event

HBV-SMARCC2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1783

Integrated sequence

CAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTG| |TAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCC

Chromosome

chr12

Cytoband

q13.2

Reference genome

Start

End

56579985/56186201 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-320a ; hsa-mir-186-5p ; hsa-let-7b-5p ; hsa-mir-5682 ; hsa-mir-585-5p ; hsa-mir-6748-3p ; hsa-mir-6890-3p ; hsa-mir-126-5p ; hsa-mir-7109-3p ; hsa-mir-214-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/1848887; hsa-let-7i/Downstream/1008303;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/56700, chr12-CpG: 76/Downstream/2723

Upstream sequence

ggattgacagattgatagctctttctcgattccgtgggtggtggtgcatggccgttcttagttggtggagcgatttgtctggttaattccgataacgaac

Downstream sequence

gagactctggcatgctaactagttacgcgacccccgagcgggtctgcgcctgccacctGTGCGGGGGCCGGCAGGACCCCGACAAGCAGCTCATGTGCGA