ZNF26 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017682
Fusion event
HBV-ZNF26 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
pre-S1/pre-S2/S;Polymerase;
Start
2848
Integrated sequence
TACATACTCTGTGGAAGGCTGGTATTTTATATAAGAGAGAAACTACCCGCAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAGYTACAGCA| |TGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAATCTTTCTGTTCCCAACCCTCTGGGATTCTTTCCCGGTCACCAGTTGGACCCTGCATT
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
133580929/133004343 (Hg38)
End
133580929/133004343 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
ZNF26
Nearest miRNA
hsa-let-7i/Upstream/422282;
Nearest TSS
ENST00000382841/Upstream/17875; ENST00000534834/Downstream/61;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/17476, chr12-CpG: 84/Downstream/32836
Upstream sequence
TGATAGAAATCAAACAGCTAATTTGACCAACCAAGGAAAAAATGTTACCAAAAATGTGACTGGTAGGTATTTGACATTCATTGTCAACTTGGAATTGTTA
Downstream sequence
ATCTCAATGAAACGGAGAAGTGAGTAAAAAAAAATAAAGCATACTCAAATCATCTAGAGTCAGCTTTCTTCTCTGCTAAATTTAGCTGAATTATTTTTTC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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