Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017683
Fusion event
HBV-RXFP2 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1671
Integrated sequence
GGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGAC| |TCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGT
Host Sequence
Chromosome
chr13
Cytoband
q13.1
Reference genome
Start
End
32371676/31797539 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-2276/Upstream/7635035; hsa-mir-1267/Downstream/7866495;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/596642, chr13-CpG: 70/Downstream/48954
Upstream sequence
AGTAAAATCATCATGTACCACAACAACAGTCTTGCATGGCTTCCACCAGAACTgtgccaggtaaagtgtgtctgaggactggggacccttcaccaactgt
Downstream sequence
tgggtacgagtctgtgaagaaattagtacttagaaacttttcacagcaatttgacagagtttctagtttacacttgtttaaataatttttaaaattgggc
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.