AGBL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017684
Fusion event
HBV-AGBL1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
core protein;
Start
1876
Integrated sequence
GAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAG| |CTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTT
Host Sequence
Chromosome
chr15
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
87064619/86521388 (Hg38)
End
87064619/86521388 (Hg38)
Location type
Intronic
Target gene
AGBL1
Nearest miRNA
hsa-mir-10393/Upstream/695658; hsa-mir-11181/Downstream/1424818;
Nearest TSS
ENST00000557528/Upstream/204215; ENST00000560803/Downstream/109748;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/680504, chr15-CpG: 36/Downstream/1734035
Upstream sequence
CATCATCAAATAATTTTCCCCCATTAACATGATGTTAAGGTTGTCATCTACCTCAAAAGATGAAAGAGAGCCTTTCAATTCTGCAATTCTGTGGCTATAC
Downstream sequence
ctatattagagttttgatggtgaccaagagactatcactgtccctgcccccaggaggctcctagtctaattgggaagtcaagagaaataaaaataaaaat
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate