VISDB Viral Integration Site DataBase

VIS ID

TVIS10017687

Fusion event

HBV-TMEM107 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1738

Integrated sequence

TGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGA| |GTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAA

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

8076825/8173507 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-652-3p ; hsa-let-7e-5p ; hsa-mir-19b-3p ; hsa-mir-335-3p ; hsa-mir-1298-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p

Nearest miRNA

hsa-mir-1253/Upstream/28436; hsa-mir-10226/Downstream/13438;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/10331, chr17-CpG: 55/Downstream/2665

Upstream sequence

tactagtttgtcaaagatgtaaacatcttctattcaagtactgaaggaatcgttcttccattttttgtgctcttcacaatgtcacagcaacaagcatgac

Downstream sequence

cacgtttcatgcatctccaatcatcatgttctaatctgccctccggaggaggaacaggtaaggattatcccacctgacgatACAGACAAACAGCCGACAT