DPP10 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017691
Fusion event
HBV-DPP10 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1801
Integrated sequence
CATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTG| |TTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
116510681/115753105 (Hg38)
End
116510681/115753105 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
DPP10
Nearest miRNA
hsa-mir-1285-2/Upstream/2031737; hsa-mir-10b/Downstream/11670432;
Nearest TSS
ENST00000437798/Upstream/312233; ENST00000473362/Downstream/61558;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/589916, chr2-CpG: 48/Downstream/2061431
Upstream sequence
TAAAAATCACTAGCAAAATAGCCCCAAATTATTCAGTGTTAGCCCTCCACTGGAAGAGTGGGATCAACATAAAATGATAATTTGTAACTAAATGACCATT
Downstream sequence
TGTATATTGTTGGTACTATATCAATGCTCTGGCTCTAAACATACATTTTAATTTTGTTTCCAAACTAGAGAATACTATATCACTATGGTTAAATGGGTAA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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