VISDB Viral Integration Site DataBase

VIS ID

TVIS10017692

Fusion event

HBV-NCKAP5 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1794

Integrated sequence

CTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAAT| |TGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTT

Chromosome

chr2

Cytoband

q21.2

Reference genome

Start

End

133776951/133019378 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-19b-3p ; hsa-mir-7977 ; hsa-mir-6892-5p ; hsa-mir-3925-3p ; hsa-mir-4267 ; hsa-mir-5588-3p ; hsa-mir-4475 ; hsa-mir-518e-3p

Nearest miRNA

hsa-mir-1285-2/Upstream/585558; hsa-mir-10b/Downstream/1107747;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/348081, chr2-CpG: 52/Downstream/246997

Upstream sequence

ACTAATCAAATGCGTTAGGTCAGAGACACTATCCCTAACTCCAGAGTAGATAAATCATTTTAATTTATGGGATAAATTCTTTTTAATTTTATCAATTTAG

Downstream sequence

ATTGGGGCAGGGGAAGGAAGGAAAAGTGGGGAATGATAAAATGGAAGCAAACTTCACCTGCTTTGAATGTCAGGGCCTGGCCTGCAGAGGACTCTGTCTC