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VISDB
Viral Integration Site DataBase
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TVIS10017693
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017693
Fusion event
HBV-CPS1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1809
Integrated sequence
AAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATT
Host Sequence
Chromosome
chr2
Cytoband
q34
Reference genome
GRCh37/hg19
Start
211423874/210559150 (Hg38)
End
211423874/210559150 (Hg38)
Location type
Intronic
Target gene
CPS1
miRNAs that regulate target gene
hsa-mir-17-5p
;
hsa-mir-3121-3p
;
hsa-mir-4255
;
hsa-mir-4709-3p
;
hsa-mir-7154-5p
;
hsa-mir-101-3p
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-6744-5p
;
hsa-mir-8060
;
hsa-mir-16-1-3p
;
hsa-mir-144-3p
;
hsa-mir-216a-5p
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-4694-3p
;
hsa-mir-6516-5p
;
hsa-mir-6738-3p
;
hsa-mir-1303
;
hsa-mir-3678-3p
;
hsa-mir-1273h-3p
;
hsa-mir-5001-3p
;
hsa-mir-4727-5p
;
hsa-mir-1200
;
hsa-mir-142-3p
;
hsa-mir-630
;
hsa-mir-146b-3p
;
hsa-mir-6799-3p
;
hsa-mir-3173-5p
;
hsa-mir-7976
;
hsa-mir-496
;
hsa-mir-302a-5p
;
hsa-mir-18a-3p
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-4682
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-4778-5p
;
hsa-mir-200b-5p
;
hsa-mir-200a-5p
;
hsa-mir-4796-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-548l
;
hsa-mir-8054
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-548c-3p
Nearest miRNA
hsa-mir-10b/Upstream/2804269; hsa-mir-1244-1/Downstream/1867113;
Nearest TSS
ENST00000437798/Upstream/2416;
ENST00000497163/Downstream/18005;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/82338
,
chr2-CpG: 86/Downstream/1978306
Upstream sequence
GAGATGCGGGTGTGTTTGGGCCGGAAGATCTTGGGGGAGTAGGTCTCCTCGGCCATCTCAGAGGTGGTGGGCTCCTCGTGCTCACGGGAGTCTCTCTCTG
Downstream sequence
CATATTTTAAAGATAGTTAAAATCATTAGGATGTAGTTACATAATGGTCAGTGAAGGGCACTGAGAACAGTCACTTTAAAGGTTAGTAGCATTATGTCCA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Sample Information
×
Sample name
229NT
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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