Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC
End
216238137/215373414 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1615255; hsa-mir-1244-1/Downstream/2527099;
Upstream sequence
CTAAAGAGCTACATCTGTACCATGTCTGCTCAGGTCCTACTTGTTGCTTTGCATCTTATGAGCAAGACCTAATTGTGGGCTCCCAAAGAAAGCAGATGAC
Downstream sequence
AAGGGAGAATAGAACCATCACATTATGTCAATGGGCTCAGCTAGTCAAGTGGAAGTCGGTCTCACCAGCAGACGCTACTGGGAGCAGGCACTTCCTCTCC
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.