Basic Information
VIS ID
TVIS10017701
Fusion event
HBV-chr3 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;Polymerase;
Start
1594
Integrated sequence
CTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCAC| |CTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGAC
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
58488193/58502466 (Hg38)
End
58488193/58502466 (Hg38)
Location type
downstream
Nearest miRNA
hsa-let-7g/Upstream/2649872; hsa-mir-12124/Downstream/2115339;
Nearest TSS
ENST00000440867/Upstream/4038; ENST00000472513/Downstream/14921;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/9919, chr3-CpG: 47/Downstream/84296
Nearby gene
KCTD6 ;
Upstream sequence
TCAAGTCATGTGATTTGTTTAGCACATAGGTTTATTTATGGTTTGATTTTTTTTAGGCAGTTATATTACTAGATTAAGCTTGTGAGGGAATGAAAATGTT
Downstream sequence
TTGATTTGAGAGGACACAGTGGGATCTTAGGTTGCAGTTTATAAGAACTGTTGCGTCACTGAAACAAGGATGGATGGAATTATTAATTTTGACTAAAAGG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate