Basic Information
VIS ID
TVIS10017705
Fusion event
HBV-LINC01192 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
core protein;X protein;
Start
1819
Integrated sequence
TATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATA
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
162990866/163273078 (Hg38)
End
162990866/163273078 (Hg38)
Location type
ncRNA
Target gene
LINC01192
Nearest miRNA
hsa-let-7g/Upstream/2868253; hsa-mir-1224/Downstream/898393;
Nearest TSS
ENST00000440867/Upstream/52937; ENST00000477099/Downstream/5495;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1900217, chr3-CpG: 20/Downstream/731184
Upstream sequence
CAATGGGAAGCCACTGACCTGTCCCAATTTCCCAAGGTTGTTATCATGGACATCATGGCTGCAGTAGAAAGTGAAGGTGAGTGTGGAAAACAGATCCCAA
Downstream sequence
TTGCTAAATAATCATTGTGTTTCCCAGTGTAGATTCTAAAACTTGGAGAATTAACTCTCGGAAAACATGTCATGATCTCACTTAATATTCTCACaaaatt
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate