ALB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017706
Fusion event
HBV-ALB integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;Polymerase;
Start
1557
Integrated sequence
CCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTG| |CCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAA
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74283998/73418281 (Hg38)
End
74283998/73418281 (Hg38)
Location type
Exonic
Target gene
ALB
miRNAs that regulate target gene
hsa-mir-492
Nearest miRNA
hsa-mir-12113/Upstream/7141353; hsa-mir-1243/Downstream/3155287;
Nearest TSS
ENST00000502981/Upstream/275; ENST00000508932/Downstream/1000;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/158868, chr4-CpG: 20/Downstream/202046
Upstream sequence
CAAGGCAACAAAAGAGCAACTGAAAGCTGTTATGGATGATTTCGCAGCTTTTGTAGAGAAGTGCTGCAAGGCTGACGATAAGGAGACCTGCTTTGCCGAG
Downstream sequence
TGAGAAGGAGAGACAAATCAAGAAACAAACGTGAGGAGTATTTCATTACTGCATGTGTTTGTAGTCTTGATAGCAAGAACTGTCAATTCAAGCTAGCAAC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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