VISDB Viral Integration Site DataBase

VIS ID

TVIS10017707

Fusion event

HBV-ADH1B integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1747

Integrated sequence

TCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGA| |GGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCAT

Chromosome

chr4

Cytoband

q23

Reference genome

Start

End

100229548/99308391 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4758-3p ; hsa-mir-3189-5p ; hsa-mir-5699-5p ; hsa-mir-5011-5p ; hsa-mir-4280 ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4705 ; hsa-mir-4666a-3p ; hsa-mir-5580-3p ; hsa-mir-34b-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-3149 ; hsa-mir-297 ; hsa-mir-568 ; hsa-mir-3924 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p

Nearest miRNA

hsa-mir-12113/Upstream/310931; hsa-mir-1243/Downstream/1932404;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/219413, chr4-CpG: 40/Downstream/255179

Upstream sequence

GGTATGTGTGAATATCCTCATGGTAGTCTGGTACTTCATTAACACTCACTGGCTTTTCATCTTCTAATATAATTGACATGTCCATAGTATGTGGTGACTC

Downstream sequence

ataCAAATTTGCAAAAATTATAAGATGATGGATAACTTGCCTGAAAGAATTGATAATTTAACAAAGTTAAGACTATGCTGGAAGTTTAAAAGACCTTTGA