VISDB Viral Integration Site DataBase

VIS ID

TVIS10017709

Fusion event

HBV-OCLN integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1825

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAAT

Chromosome

chr5

Cytoband

q13.2

Reference genome

Start

End

68843664/69547837 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-340-5p ; hsa-mir-548t-5p ; hsa-mir-3148 ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-4491 ; hsa-mir-4657 ; hsa-mir-548az-5p ; hsa-mir-6833-5p ; hsa-mir-8062 ; hsa-mir-1295a ; hsa-mir-5704 ; hsa-mir-3941 ; hsa-mir-216b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-576-3p ; hsa-mir-3190-3p ; hsa-mir-6124 ; hsa-mir-299-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-5692a ; hsa-mir-4755-3p ; hsa-mir-301a-5p ; hsa-mir-301b-5p ; hsa-mir-345-5p ; hsa-mir-4293 ; hsa-mir-4305 ; hsa-mir-4433a-3p ; hsa-mir-4434 ; hsa-mir-4459 ; hsa-mir-4516 ; hsa-mir-4531 ; hsa-mir-4768-3p ; hsa-mir-4777-5p ; hsa-mir-4786-5p ; hsa-mir-4802-3p ; hsa-mir-518d-5p ; hsa-mir-518e-5p ; hsa-mir-518f-5p ; hsa-mir-519a-5p ; hsa-mir-519b-5p ; hsa-mir-519c-5p ; hsa-mir-520c-5p ; hsa-mir-522-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-5703 ; hsa-mir-6771-3p ; hsa-mir-6849-3p ; hsa-mir-1228-5p ; hsa-mir-1285-3p ; hsa-mir-3187-5p ; hsa-mir-378g ; hsa-mir-4314 ; hsa-mir-4486 ; hsa-mir-5189-5p ; hsa-mir-5579-5p ; hsa-mir-612 ; hsa-mir-6860

Nearest miRNA

hsa-mir-10397/Upstream/9844134; hsa-mir-103a-1/Downstream/2621630;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/53841, chr5-CpG: 39/Downstream/12145

Upstream sequence

GAATCCTGACCAGATAGGTAGGATGACAATTGAATTCTATCACTGTACTAAGCCCTCAGTTAAACTTGGTAAAGTTACTTAGATAAACTATTTTCACCCC

Downstream sequence

ACCCAACCAGCTTTATTATCTTTGAGGAAGGAGCATTGAATTTTATGTCTGCTAAGGATACATATGTAGTCATTTTCTCTCTCACCTTTTAGGGAATATC