VISDB Viral Integration Site DataBase

VIS ID

TVIS10017712

Fusion event

HBV-TSPYL1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;

Start

1843

Integrated sequence

GGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATC| |TCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGT

Chromosome

chr6

Cytoband

q22.1

Reference genome

Start

End

116599068/116277905 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-320c ; hsa-mir-877-3p ; hsa-mir-92b-3p ; hsa-mir-1260b ; hsa-mir-7844-5p ; hsa-mir-382-5p ; hsa-mir-142-3p ; hsa-mir-526b-5p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-6854-5p ; hsa-mir-580-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-539-5p ; hsa-mir-3123 ; hsa-mir-4503 ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-6792-5p ; hsa-mir-16-1-3p ; hsa-mir-3681-3p ; hsa-mir-6501-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-144-3p ; hsa-mir-450a-1-3p ; hsa-mir-4425 ; hsa-mir-8065 ; hsa-mir-6825-5p ; hsa-mir-585-3p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6069 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-3179 ; hsa-mir-3185 ; hsa-mir-4259 ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-3154 ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-6849-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-5586-5p ; hsa-mir-6746-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-665 ; hsa-mir-1273e ; hsa-mir-3175 ; hsa-mir-4722-5p ; hsa-mir-7160-5p ; hsa-mir-1827 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-4649-3p ; hsa-mir-5690 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-1292-3p ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-495-5p ; hsa-mir-6087 ; hsa-mir-6499-3p ; hsa-mir-6516-5p

Nearest miRNA

hsa-mir-10398/Upstream/9493685; hsa-mir-1202/Downstream/2791142;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/23701, chr6-CpG: 54/Downstream/1502

Upstream sequence

AAAAATATTCAGAATCTGGTAAAAAAAACTAACTTTAGTTACTTCTAAATTGAAGATTAATTCTAGATGATTTAATAGTCAAACATTTTTGGTTGTtgag

Downstream sequence

ctcaaaaaaaaaaaaaaaaaaaaaaaaaaGGAAAACAGGGAGAGAGAGGGACCTTGGCAGGAGCCAATGTAGGGCAGGTAGCAATAGAAAGTGACTAGAG