Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017714
Fusion event
HBV-PLG integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
core protein;
Start
2122
Integrated sequence
CTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTAAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGT| |AATTTGGAAGACCCAGCATCCAGGGAATTAGTAGTAAGCTATGTCAATGTTAATATGGGCCTAAAAATCAGACAACTATTGTGGTTTCACATTTCCTGTC
Host Sequence
Chromosome
chr6
Cytoband
q26
Reference genome
End
161124723/160703691 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/1938938; hsa-mir-1913/Downstream/5805663;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/24267, chr6-CpG: 51/Downstream/63361
Upstream sequence
AAAAATATTCAGAATCTGGTAAAAAAAACTAACTTTAGTTACTTCTAAATTGAAGATTAATTCTAGATGATTTAATAGTCAAACATTTTTGGTTGTtgag
Downstream sequence
TTTTGTAAGAAATTGGTGTATGTTGGGGGGTATGAATATTATATTTCAATGCATGGAAACTAGGACATAGATCACTATGAACTTATTCAGTGGGCTACAC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.