Fusion event
HBV-HDAC9 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;
Integrated sequence
GTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGC| |CTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTC
End
18383238/18343615 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1302-6/Upstream/216306; hsa-mir-10399/Downstream/1361743;
Upstream sequence
ATGTCCAAACTTTGTGTATTTCAGTTTTAAAAAGAATCTGCAGAATATAATTCTTGGCAATCAGCCAGTAAGTGCCTACACACTTTTCTAAGCACAATTA
Downstream sequence
CTTAATGTACATTTTTAAAAACAGCAAAATATAAAACATAGAAATAAATTTCTACCTTGGATCTAACTAGAGAGCTCTTTTGCCTTCTCTACTTTTCTTG
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.