Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017719
Fusion event
HBV-ARHGAP36 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
458
Integrated sequence
TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC
Host Sequence
Chromosome
chrX
Cytoband
q26.1
Reference genome
End
130215778/131081804 (Hg38)
Location type
Exonic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7f-2/Upstream/9710751; hsa-mir-105-1/Downstream/3087574;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/8323, chrX-CpG: 63/Downstream/552
Upstream sequence
GAAATACAATTCCTAAAATATCAACTTTTCCAGAAAACCGTGGCTACACAATAATGCATTGCCTCTATCATGTTAGAACGTGCATTAGACTCAAATACAA
Downstream sequence
CGAAGATGGTATCGATACACAGCCTCTCTGAGCTGGAGCGTCTGAAGCTGCAAGAGACTGCTTACCACGAACTCGTGGCCAGACATTTCCTCTCCGAATT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.