VISDB Viral Integration Site DataBase

VIS ID

TVIS10017725

Fusion event

HBV-PTPN14 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

3106

Integrated sequence

GCGGCACACCAGGTAGGAGTGGGATCCTTCGGGCCAGGGTTCACTCCACCACACGGCAATCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATATTGACAA| |CAGTACCAGCAGCGCCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGACAGCCTACTCCCATCTCTCCACCTCTAAGAGACAGTCATCCTCAGGCCAT

Chromosome

chr1

Cytoband

q41

Reference genome

Start

End

214662304/214488961 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-324-3p ; hsa-mir-590-5p ; hsa-mir-3190-3p ; hsa-mir-4491 ; hsa-mir-4657 ; hsa-mir-6833-5p ; hsa-mir-218-5p ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-7977 ; hsa-mir-5579-3p ; hsa-mir-92a-1-5p ; hsa-mir-5703 ; hsa-mir-765 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6770-5p ; hsa-mir-4699-5p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4662a-3p ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-302c-5p ; hsa-mir-3143 ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-342-3p ; hsa-mir-1285-5p ; hsa-mir-5582-5p ; hsa-mir-451b ; hsa-mir-5580-3p ; hsa-mir-124-3p ; hsa-mir-4484 ; hsa-mir-6768-3p ; hsa-mir-130a-5p ; hsa-mir-23a-3p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-494-3p ; hsa-mir-548aw ; hsa-mir-6867-3p ; hsa-mir-642a-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1236-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-500a-5p ; hsa-mir-4668-3p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-629-5p ; hsa-mir-302a-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-4307 ; hsa-mir-299-3p ; hsa-mir-33a-3p ; hsa-mir-217 ; hsa-mir-1182 ; hsa-mir-1207-5p ; hsa-mir-1267 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-1827 ; hsa-mir-197-3p ; hsa-mir-3149 ; hsa-mir-3167 ; hsa-mir-3184-3p ; hsa-mir-3612 ; hsa-mir-3664-5p ; hsa-mir-3672 ; hsa-mir-367-5p ; hsa-mir-411-5p ; hsa-mir-4443 ; hsa-mir-4524a-3p ; hsa-mir-4639-3p ; hsa-mir-4763-3p ; hsa-mir-483-5p ; hsa-mir-5096 ; hsa-mir-650 ; hsa-mir-6515-5p ; hsa-mir-6794-3p ; hsa-mir-6808-5p ; hsa-mir-6832-5p ; hsa-mir-6864-3p ; hsa-mir-6893-5p ; hsa-mir-7850-5p ; hsa-mir-8055 ; hsa-mir-876-5p ; hsa-mir-940

Nearest miRNA

hsa-mir-101-1/Upstream/2411276; hsa-mir-1182/Downstream/5628892;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/104862, chr1-CpG: 124/Downstream/61800

Upstream sequence

AAATGGGGGCTGTGTCATTTCCCAACAGGCAGCCAGCCCCAGCATGTAGTTGGTGACAGAGCAAAAGACCGCCTCCTTGGGCAAAGCGTTACCCCAGAAC

Downstream sequence

AGGCCTTTCACTCAGAGGATTGAAGCCCAAGacttcctaagtgctgtgtggccttagccaagtcgctttccttctctgtttccctctctgtaaagtggca