VISDB Viral Integration Site DataBase

VIS ID

TVIS10017727

Fusion event

HBV-SEMA6D integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1805

Integrated sequence

CTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA

Chromosome

chr15

Cytoband

q21.1

Reference genome

Start

End

47674035/47381838 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-130a-5p ; hsa-mir-23c ; hsa-mir-3662 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4506 ; hsa-mir-7-5p ; hsa-mir-5003-5p ; hsa-mir-8485 ; hsa-mir-3529-3p ; hsa-mir-589-3p ; hsa-mir-8068 ; hsa-mir-1225-5p ; hsa-mir-10b-3p ; hsa-mir-1278 ; hsa-mir-1911-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-3182 ; hsa-mir-361-5p ; hsa-mir-3617-3p ; hsa-mir-374a-3p ; hsa-mir-4303 ; hsa-mir-4490 ; hsa-mir-452-5p ; hsa-mir-4659a-3p ; hsa-mir-4659b-3p ; hsa-mir-4676-3p ; hsa-mir-4682 ; hsa-mir-513a-5p ; hsa-mir-6736-3p ; hsa-mir-892c-3p ; hsa-mir-4433a-3p ; hsa-mir-4433b-3p ; hsa-mir-4496 ; hsa-mir-4722-5p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-6165

Nearest miRNA

hsa-mir-10393/Upstream/1948709; hsa-mir-11181/Downstream/1787232;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/196536, chr15-CpG: 129/Downstream/335383

Upstream sequence

TACAGTAATAGCAAAGAAAGTCTTAAAGATGATTTAGCCCATGGCAAGGAAATATATGGGACTCTTGTTTGAATATAAACACTCACAGAATTCCAGTTTC

Downstream sequence

TTGGGAACATATGGGCTAACTCCTCTTGTGCATAGTTAGAAATGGTCTTTGTCCTACTTGGCCCCTCTCTGCTCttcattcagtgaagatatgttgaata