VISDB Viral Integration Site DataBase

VIS ID

TVIS10017728

Fusion event

HBV-NEO1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

core protein;X protein;

Start

1821

Integrated sequence

TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAA

Chromosome

chr15

Cytoband

q24.1

Reference genome

Start

End

73577279/73284938 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-590-3p ; hsa-mir-32-5p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-183-5p ; hsa-mir-18a-5p ; hsa-mir-6793-3p ; hsa-mir-4775 ; hsa-mir-6771-3p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-10393/Upstream/697625; hsa-mir-11181/Downstream/14972;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/231910, chr15-CpG: 29/Downstream/33894

Upstream sequence

AAACAAAACAAAACAGAAATCATATCTGATTCTGCATATGAATGCTGGTAAatttattctttccaaattatttatccaatatcaactcttgacagagtta

Downstream sequence

CATTTTTTTTTCTACTCTAGAACTTTTCTTCAAGCCTCTTTATTTGGCATTTAATATTTATCTATCTATGAACTTGATTTTATATCAGTTTTAGAAATAT