Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017729
Fusion event
HBV-HP integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
706
Integrated sequence
CATCCCATCATCTTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTA| |GGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAATCCCTTTTTACCGCTGTTACCAA
Host Sequence
Chromosome
chr16
Cytoband
q22.2
Reference genome
Start
End
72094565/72060666 (Hg38)
Location type
Exonic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/2030244; hsa-mir-11401/Downstream/4808270;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/51677, chr16-CpG: 15/Downstream/32564
Upstream sequence
CTGCTATGGCGATGCGGGCAGTGCCTTTGCCGTTCACGACCTGGAGGAGGACACCTGGTATGCGACTGGGATCTTAAGCTTTGATAAGAGCTGTGCTGTG
Downstream sequence
TACTGAATGAACACACCTTCTGTGCTGGCATGTCTAAGTACCAAGAAGACACCTGCTATGGCGATGCGGGCAGTGCCTTTGCCGTTCACGACCTGGAGGA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.