Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017736
Fusion event
HBV-GP6 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Region type
X protein;
Start
1803
Integrated sequence
TACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTT| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
Start
End
55548409/55037041 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7e/Upstream/391658; hsa-mir-10394/Downstream/86184;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3487, chr19-CpG: 69/Downstream/25729
Upstream sequence
GCAGCAGAAGGTGGCAGCTTCCATGCCGGTGAGTGTGGTCCCTGGGCCCAGCGGCACACCCAGCCATCCAGCCTCCATTCTTTGCAACCCCCTAACCTTC
Downstream sequence
TACATCCATGGATGGATAATGAATGAGAGGTTGTTTATATTCACAGTTAACCCTCTCATCTCCAGTAATGCAACCATCTTCTTCCTGCTTAGCCTTTTGG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.